Lead end-to-end clinical trial execution. ICON seeks a Clinical Trial Manager II (CTM II) to manage studies from start-up to close-out. 5+ yrs clinical project management exp. req. Apply today.
Lead with Impact: Drive Clinical Trials from Strategy to Delivery
ICON plc is a world-leading healthcare intelligence and clinical research organization. From molecule to medicine, we advance clinical research providing outsourced services to pharmaceutical, biotechnology, and medical device organizations.
We are seeking an accomplished Clinical Trial Manager II (CTM II) to take full accountability for the strategic and operational delivery of global clinical trials. In this pivotal role, you will be the primary leader, ensuring studies are executed on time, within budget, and to the highest standards of quality and compliance. You will translate protocols into action, navigate complex challenges, and lead cross-functional teams to deliver the robust data needed to advance new therapies.
Your Mission: The Single Point of Accountability for Trial Success
As a Clinical Trial Manager II, you will own the study from start-up through close-out. You will leverage your deep operational expertise to develop project strategy, manage risks, and drive performance, ensuring every milestone is met and every deliverable exceeds expectations.
Key Responsibilities
1. Strategic Study Leadership & Planning
- Serve as the primary leader and single point of accountability for assigned clinical trial(s), developing and executing comprehensive project plans, timelines, and budgets.
- Collaborate with cross-functional teams (Clinical Operations, Data Management, Regulatory, Safety) to develop and implement robust clinical trial protocols and operational plans.
- Lead study start-up activities, including site identification, feasibility, and activation, to ensure rapid enrollment.
2. Operational Execution & Oversight
- Oversee the day-to-day operations of clinical trials, proactively managing site performance, patient recruitment, and data quality.
- Monitor study progress against key metrics, analyzing data to identify trends, anticipate risks, and implement effective corrective and preventive actions (CAPA).
- Manage vendor selection, contracts, and performance (e.g., Central Labs, IRT, Imaging) to ensure seamless service delivery.
3. Stakeholder Management & Problem-Solving
- Act as the main point of contact for the sponsor, providing transparent communication on study status, risks, and budget.
- Effectively communicate with and align internal and external stakeholders to foster strong partnerships and resolve complex issues.
- Ensure all trial activities are conducted in full compliance with ICH-GCP guidelines, SOPs, and global regulatory requirements.
Who You Are: The Ideal Candidate
You are a proactive, results-driven leader with a proven track record of managing complex clinical trials. You thrive on responsibility, excel in a matrix environment, and are skilled at motivating teams to achieve a common goal under pressure.
Your Required Foundation:
- Bachelor’s degree in Life Sciences, Nursing, or a related field. An advanced degree is a plus.
- Minimum of 5+ years of direct experience in clinical trial management within a pharmaceutical, biotech, or global CRO environment. (Note: Replace [X] with a specific number, e.g., 5).
- Proven expertise in managing all phases of clinical trial execution (start-up, maintenance, close-out) for global studies.
- Strong understanding of ICH-GCP and major regulatory agency requirements (FDA, EMA, etc.).
- Exceptional financial acumen with experience managing multi-million-dollar study budgets.
- Outstanding analytical, problem-solving, and decision-making skills.
- Excellent communication, interpersonal, and leadership skills, with the ability to influence without direct authority.
What Sets You Apart (Preferred):
- Experience in specific therapeutic areas (e.g., Oncology, Immunology, CNS).
- Prior line management or mentoring experience.
- Proven success in a client-facing or strategic partnership role.
- Professional project management certification (PMP, PRINCE2).
Why Advance Your Career as a CTM II at ICON?
1. Lead with Autonomy & Visibility
- Take on high-visibility leadership roles with end-to-end accountability for critical studies.
- Gain experience across a diverse portfolio of sponsors and therapeutic areas.
2. Accelerated Career Growth
- Clear and structured progression pathway to Senior CTM, Associate Director, and Director-level positions within Project Leadership.
- Access to advanced leadership training and professional development programs.
3. Comprehensive Benefits & Global Network
- Competitive salary and significant performance-based bonus potential.
- Generous annual leave entitlements and flexible working arrangements.
- Comprehensive health, life, and disability insurance for you and your family.
- Competitive retirement planning offerings.
- Global Employee Assistance Programme and a supportive, collaborative company culture.
Join a Culture of Inclusive Leadership
At ICON, we believe diverse leadership drives better outcomes. We are dedicated to providing an inclusive, accessible environment and encourage all qualified candidates to apply.
Ready to be the strategic leader who turns clinical protocols into patient-ready therapies?
If you have the expertise to manage complexity and the drive to deliver excellence, we want to hear from you. Apply now.
