Scientist role at Lambda CRO. Independently execute mAb upstream process dev using AMBR, lab bioreactors (5L-10L) & aseptic cell culture. MSc/MTech in Biotech + 2-6 yrs exp in mammalian upstream processing req. #UpstreamProcessing #Biologics #CellCulture #Bioreactor #AhmedabadJobs #CRO
Develop Next-Generation Biologics: Upstream Process Scientist
Organisational Overview
Lambda Therapeutic Research is a leading global Clinical Research Organization (CRO) headquartered in Ahmedabad, India, with a global footprint across the US, UK, and Europe. With over 1500 employees, we deliver full-spectrum clinical trial solutions powered by two decades of expertise, innovative technologies, and a commitment to quality.
Delivering the best accomplished by hiring the best. We are looking for qualified, energetic individuals with a desire for excellence to join our team.
The Role
We are seeking a skilled and independent Scientist to join our Process Sciences group, focusing on monoclonal antibody (mAb) upstream process development. In this hands-on laboratory role, you will independently plan and execute aseptic cell culture and bioreactor experiments to develop and optimize upstream processes for clinical-grade drug substances. Your technical expertise will be critical in advancing our clients' biologics pipeline.
Job Details: Technical Execution & Development
You will be the technical expert responsible for executing core upstream development activities with a high degree of proficiency.
Key Responsibilities:
- Aseptic Cell Culture Operations: Demonstrate skilled and highly proficient aseptic handling for mammalian cell culture.
- Bioreactor Process Development: Independently operate disposable mini-bioreactors (AMBR 15/250), glass lab bioreactors (5L, 10L), and shake flasks for clone/media/feed screening and process optimization.
- Process Scale-Up & Analysis: Perform upstream process optimization at laboratory scale. Work proficiently with automated bioanalyzers and cell counters for in-process analysis.
- Experimental Design & Documentation: Apply knowledge of basic Design of Experiments (DOE), data trending, and analysis. Ensure meticulous documentation and QA compliance for data presentation.
- GLP/GMP Understanding: Develop mAb upstream processes with an understanding of GLP/GMP suite requirements for clinical-grade production.
- Media & Buffer Preparation: Prepare media, feeds, supplements, and perform sterile filtration.
Who You Are: The Hands-On Process Developer
You are a technically driven scientist with a solid foundation in mammalian cell culture and a passion for hands-on laboratory work.
Your Profile:
Education:
- M.Sc / M.Tech / Ph.D. in Biotechnology, Biochemistry, Microbiology, or an equivalent field.
Experience:
- 2 to 6 years of direct, hands-on experience developing mAb upstream processes from mammalian cell lines within a biopharma, biotech, or relevant CRO/CDMO environment.
- Must-have hands-on experience with:
- AMBR 15 and/or AMBR 250 systems.
- Disposable and glass laboratory-scale bioreactors (5L, 10L).
- Aseptic cell culture techniques.
- Understanding of basic DOE principles and data analysis.
- Preference will be given to candidates with prior experience in leading a small team within an upstream processing unit.
Why Build Your Career at Lambda?
1. Impact on Global Drug Development
- Contribute directly to the development of therapeutic antibodies for clients worldwide.
- Work on diverse projects across various therapeutic areas.
2. Technical Growth & Expertise
- Gain hands-on experience with state-of-the-art equipment (AMBR systems, automated analyzers) in a fast-paced development environment.
- Clear pathway for career progression into senior scientific or team leadership roles.
3. Be Part of a Global Leader
- Join a respected, growing global CRO with a strong scientific reputation.
- Collaborate with cross-functional teams (Downstream, Analytics) on integrated biologics projects.
Ready to Culture Innovation in Biologics Development?
If you are an upstream processing scientist ready to apply your technical skills to meaningful projects in a global CRO, we encourage you to apply.
Apply now for the Scientist - Upstream Process Development position at Lambda Therapeutic Research in Ahmedabad.
